Diffuse Lewy body disease presenting with a supranuclear gaze palsy.

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Diffuse Lewy body disease presenting with a supranuclear gaze palsy.

A patient with diffuse Lewy body disease presented with supranuclear vertical and horizontal ophthalmoplegia, dementia, axial rigidity and falls, bradykinesia and pyramidal signs. This broadens the clinical presentation of this pathological diagnosis and re-emphasises the heterogeneity of patients diagnosed clinically as progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome).

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[Diffuse Lewy body disease].

Diffuse Lewy body disease (DLBD) has been studied from various viewpoints and, although clinical diagnostic criteria for DLBD have been proposed, diagnosis remains difficult. DLBD has been reported to be the second most common form of dementia in the aged, following Alzheimer-type dementia. It has, however, been clinically under-diagnosed. Therefore, the search for diagnostic markers for DLBD m...

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Vertical supranuclear gaze palsy with secondary syphilis.

A 48-year-old man presented with a vertical gaze palsy associated with secondary syphilis. It is suggested that the eye movement disorder is due to syphilitic endarteritis in the mesodiencephalic region.

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Progressive supranuclear palsy presenting with dynamic aphasia.

BACKGROUND Progressive supranuclear palsy (PSP) is an akinetic-rigid syndrome of unknown aetiology which usually presents with a combination of unsteadiness, bradykinesia, and disordered eye movement. Speech often becomes dysarthric but language disorders are not well recognised. METHODS Three patients with PSP (pathologically confirmed in two) are reported in which the presenting symptoms we...

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Diffuse Lewy body disease: an autopsy case.

A 67-year-old male patient initially showed memory disturbance followed by tremors a year later. The symptoms rapidly aggravated to dementia and Parkinsonian symptoms, and the patient died 2 years and 6 months after the onset at the age of 69 years and 5 months. Autopsy revealed numerous senile plaques in the cerebral cortex and Alzheimer's neurofibrillary tangles in the inferior temporal lobe ...

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ژورنال

عنوان ژورنال: Journal of Neurology, Neurosurgery & Psychiatry

سال: 1991

ISSN: 0022-3050

DOI: 10.1136/jnnp.54.2.159